VALIDATION OF THE NEW EPIC DNA METHYLATION MICROARRAY (900K EPIC V2) FOR HIGH-THROUGHPUT PROFILING OF THE HUMAN DNA METHYLOME

Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome

DNA methylation, one of the best characterized epigenetic marks in the human genome, plays a click here pivotal role in gene transcription regulation and other biological processes in humans.On top of that, the DNA methylome undergoes profound changes in cancer and other disorders.However, large-scale and population-based studies are limited by hig

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The effect of esmolol on corrected-QT interval, corrected-QT interval dispersion changes seen during anesthesia induction in hypertensive patients taking an angiotensin-converting enzyme inhibitor

BACKGROUND AND OBJECTIVES: The importance of minimizing the exaggerated sympatho-adrenergic responses and QT interval and QT interval dispersion changes that may develop due to laryngoscopy and tracheal intubation during anesthesia induction in the hypertensive patients is clear.Esmolol decreases the hemodynamic response to laryngoscopy and intubat

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Perceived impact of digital health technology on health professionals and their work: A qualitative study in Southern Ghana

Background Digital health technology (DHT) has become an essential part of an effective and efficient healthcare information system.Although DHT promises great potential it does not always meet the expectation of users.Often, in low- and middle-income countries (LMICs), the implemented DHT does not function as intended and impacts negatively on hea

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